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RHUGM-CSF-50µg   GENTAUR HEADQUARTERS  +32 1641 4407  +32 1650 9045 

 rHuIL-2-3MIU huIFNa-2a huIFNa-2b Mouse GM-CSF rHuIL-4 GMPhuIL-4-50µg RHUGMCSF-300µg RHUGM-CSF-50µg huG-CSF-300µg huIL-6 -50 µg rhug-csf 300µg rhug-csf_75µg rhuil-1b-100µg


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Molgramostim (rHuGM-CSF)


l        Description

Molgramostim is a human granulocyte macrophage colony-stimulating factor (GM-CSF), produced by recombinant DNA technology from E.coli. It is 127 amino acid protein, non-glycosylated, and has a molecular weight of approximately 14.5kD. The amino acid sequence is identical to the natural, except for the addition of an N-terminal methionine.


l        Indication

1.      In patients receiving myelosuppressive therapy ( cancer chemotherapy ) to reduce the severity of neutropenia, thereby reducing the risk of infection and allowing better adherence to the chemotherapeutic regimen;

2.      In patients undergoing autologous or syngeneic bone marrow transplantation to accelerate myeloid recovery (Molgramostim does not improve overall survival or increase time to relapse);



l        Pharmaceutical particulars

Sterile, white and preservative-free lyophilized powder to be reconstituted with a diluent (Sterile Water for Injection) for injection, presented in vials.

Dosage: 75μg/vial, 150μg/vial, 300μg/vial and 400μg/vial

Reference: Current European Pharmacopoeia and Internal Requirements

Specific activity: ≥1.0×107IU/mg

Purity (HPLC, SDS-PAGE): ≥98%


l      Composition

Active ingredients: Molgramostim (rHuGM-CSF)

Inactive ingredients: Mannitol, Macrogol 4000, Human Albumin, Dibasic Sodium phosphate and Monobasic Potassium Phosphate.


l        Shelf life and storage conditions


 Finished formulation

 Store at 2-8 for 3 years

 API (Concentrated solution)

 Store at -70 for 12 months



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Last modified: 06/25/09